The Well-Fed State: Insulin-Dependent Enzyme Regulation
From Metabolism Made Easy by A J Ghalayini, Ph.D.
April 21, 2026 · 8 min
About this episode
This episode discusses how insulin affects enzyme activity in the well-fed state through various mechanisms.
In the well-fed state, insulin will affect enzyme activity through at least 3 distinct mechanisms: 1. Allosteric regaulation; 2. Covalent modification, and 3. Upregulation of enzymes. These effects will activate both glycolysis and glycogen synthesis.
People in this episode
Host: A J Ghalayini, Ph.D.
Topics covered
- insulin regulation
- enzyme activity
- glycolysis
- glycogen synthesis
- metabolism
Keywords
- insulin
- enzyme regulation
- glycolysis
- glycogen synthesis
- metabolism
Mentioned in this episode
Organizations: insulin, glycolysis, glycogen
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