The REAL Science Behind Creatine

The REAL Science Behind Creatine

From Mindful Paths Podcast by Nick Day & Hari Kalymnios

December 17, 2025 · 57 min · Season 1 · Episode 80

About this episode

Nick and Hari explore the science behind creatine, addressing myths and its benefits for physical and brain health.

In this episode of Mindful Paths, Nick and Hari take a clear, research grounded look at creatine and why it may be one of the most misunderstood yet evidence backed supplements for both physical performance and brain health. Is creatine really just for bodybuilders, or has it been unfairly dismissed because of outdated myths and poor marketing? Nick and Hari break down what creatine actually does in the body, how it supports ATP production, and why decades of research continue to show benefits for strength, power, recovery, and training quality. They also unpack common concerns around water weight, kidney health, bloating, and hair loss, explaining what the science actually says and who should be cautious. The conversation compares creatine monohydrate to newer forms like capsules and serums, discusses loading versus steady dosing, and explains why simplicity, testing, and cost effectiveness matter more than flashy supplement claims. Zooming out, the episode uses creatine as a lens to question modern supplement culture and lifestyle driven deficiencies. Through reflections on aging, cognition, stress, and a desert island thought experiment, Nick and Hari explore which supplements…

People in this episode

Hosts: Nick Day, Hari Kalymnios

Topics covered

  • creatine
  • supplements
  • physical performance
  • brain health
  • myths
  • research

Keywords

  • creatine
  • supplements
  • ATP production
  • strength
  • power
  • recovery
  • health

Mentioned in this episode

Organizations: LinkedIn, T4M Coach

Products: creatine

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