David Sinclair: The GLP-1 Side Effect No One Talks About, What AI Found in His Lab, and Reversing Blindness | Q&A EP #251

David Sinclair: The GLP-1 Side Effect No One Talks About, What AI Found in His Lab, and Reversing Blindness | Q&A EP #251

From Moonshots with Peter Diamandis by PHD Ventures

April 28, 2026 · 27 min

About this episode

This episode discusses longevity and the impact of AI on health and drug discovery with David Sinclair.

This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/ This Q&A is about longevity, and especially how David Sinclair sees AI speeding up drug discovery, biological-age reversal, and the future of healthspan. It also covers GLP-1s, telomeres, genetics, muscle preservation, hormone replacement, indoor environment, and the role of mindset in aging well. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter _ Connect…

People in this episode

Host: Peter H. Diamandis, MD

Guest: David A. Sinclair, A.O., Ph.D.

Topics covered

  • longevity
  • AI in drug discovery
  • biological-age reversal
  • healthspan
  • GLP-1s
  • aging well

Keywords

  • longevity
  • AI
  • drug discovery
  • healthspan
  • GLP-1
  • aging
  • biotech

Mentioned in this episode

Organizations: Harvard Medical School, XPRIZE, Singularity University, ZeroG, A360

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