Neuro-Oncology Nugget: GT-20 Phase 1 Trial — Personalized Neoantigen DNA Vaccine for MGMT Unmethylated Glioblastoma

Neuro-Oncology Nugget: GT-20 Phase 1 Trial — Personalized Neoantigen DNA Vaccine for MGMT Unmethylated Glioblastoma

May 29, 2026 · 3 min

About this episode

Shahad Abdulsahib discusses a phase 1 clinical trial for a personalized DNA vaccine targeting glioblastoma.

Host/Interviewee: ç, PhD Candidate, UT Health San Antonio Description: Shahad Abdulsahib discusses the GT-20 phase 1 clinical trial evaluating GNOS-PV01, a personalized multivalent neoantigen DNA vaccine administered following surgical resection and radiation in patients with MGMT unmethylated glioblastoma, with findings published in Nature Cancer on May 12th, 2026.

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