Epstein-Barr Virus Antibodies to Differentiate MS From Other Neuroinflammatory Diseases - Part 2

About this episode

Dr. Justin Abbatemarco and Dr. Paulus Rommer discuss applying study results on Epstein-Barr Virus antibodies in clinical practice to differentiate multiple sclerosis from other neuroinflammatory diseases.

In the second part of this series, Dr. Justin Abbatemarco and Dr. Paulus Rommer discuss how to apply these study results into clinical practice. Show citation: Vietzen H, Kühner LM, Berger SM, et al. Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases. JAMA Neurol . Published online March 9, 2026. doi: 10.1001/jamaneurol.2026.0240 Show transcript: Dr. Justin Abbatemarco: Hello and welcome back. This is Justin Abbatemarco, and we're finishing up our interview with Paulus Rommer on his article on JAMA Neurology, Epstein-Barr Virus Antibodies that differentiate multiple sclerosis from other Neuroinflammatory Diseases. Paulus, can we talk about how we would apply your results into clinical practice right now? Dr. Paulus Rommer: The persistent high apnea antibody responses are a hallmark of multiple sclerosis. And in our micro center study, we found that the singular measurement is not sufficient to differentiate multiple sclerosis from other related disorders like MOGAD or NMOSD, but it's the repeated high levels over time. We see them in about 95% of our MS patients, but really rarely in MOGAD or NMOSD. So this persistent high…

People in this episode

Host: Dr. Justin Abbatemarco

Guest: Dr. Paulus Rommer

Topics covered

• Epstein-Barr Virus
• Multiple Sclerosis
• Neuroinflammatory Diseases
• Clinical Practice
• Antibody Responses

Keywords

• Epstein-Barr Virus
• Multiple Sclerosis
• Neuroinflammatory Diseases
• Antibodies
• Clinical Practice
• Diagnosis
• MOGAD
• NMOSD

Mentioned in this episode

Organizations: American Academy of Neurology

Books & works: JAMA Neurol, Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases

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