Rewriting human aging with Physics and AI with Dr. Peter Fedichev of Gero (Part 1)
About this episode
Dr. Peter Fedichev discusses the intersection of physics and AI in combating aging and age-related diseases.
Dr. Peter Fedichev is the co-founder and CEO of GERO , a Singapore-based biotech startup that uses physics-informed AI and massive human health datasets to discover drugs aimed at slowing down aging and treating age-related diseases. In this episode, explains his transition from a decade in theoretical physics to longevity biotech, motivated by applying physics tools to complex living systems and discoveries like the naked mole rat’s lack of mortality acceleration. He contrasts biology’s case-control, fact-collecting culture with physics’ search for universal variables, arguing aging is a universal, chronic-process problem well suited to physics-style modeling. Peter describes Gero’s approach as building predictive, generative AI models from large-scale medical records and omics data to capture the “equations of motion” of health over time. He critiques hallmark-of-aging narratives and emphasizes “functional decline” (functional span) over healthspan, noting very old people can be disease-free yet severely impaired. Using thermodynamics as an analogy, he argues aging involves entropy-like, stochastic damage that is hard to reverse but potentially possible to slow or stop by…
People in this episode
Host: John Joson Ng
Guest: Dr. Peter Fedichev
Topics covered
- aging
- biotech
- AI
- health
- physics
- longevity
Keywords
- aging
- biotech
- AI
- health dynamics
- functional decline
- thermodynamics
- longevity
Mentioned in this episode
Organizations: GERO
More episodes of Nucleate Singapore Pulse
- Charting Singapore's Biotech Pipeline with Dr. Katherine Wang of A*STAR's STDR
- Rewriting human aging with Physics and AI with Dr. Peter Fedichev of Gero (Part 2)
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