On AI and Psychotherapy: Bringing Innovation to Everyday Clinical Practice

On AI and Psychotherapy: Bringing Innovation to Everyday Clinical Practice

From On the Mind with The Weill Cornell Medicine Department of Psychiatry by Weill Cornell Medicine

December 8, 2025

About this episode

Dr. Daniel Knoepflmacher interviews Dr. Nili Solomonov about the role of AI in psychotherapy and her innovative research on effective mental healthcare treatments.

In this episode, host Dr. Daniel Knoepflmacher speaks with Dr. Nili Solomonov about her innovative psychotherapy research and the emerging role of artificial intelligence in mental healthcare. Dr. Solomonov describes how her lab harnesses the computational power of AI to investigate mechanisms underlying effective psychotherapy. Her findings have led to the creation of an evidence-based treatment modality (called Engage and Connect) initially designed for older adults. Their conversation explores how research can expand access to effective psychological treatments, the ways Engage and Connect has been adapted for diverse patient populations, and the complex landscape of AI in mental health, including its significant risks and potential clinical applications. Learn more about the American Psychological Association’s health advisory on the use of generative AI chatbots and wellness applications for mental health Learn more about Dr. Solomonov’s research

People in this episode

Host: Dr. Daniel Knoepflmacher

Guest: Dr. Nili Solomonov

Topics covered

  • artificial intelligence
  • psychotherapy
  • mental healthcare
  • evidence-based treatment
  • access to psychological treatments

Keywords

  • AI
  • psychotherapy
  • mental health
  • evidence-based treatment
  • Engage and Connect
  • Dr. Nili Solomonov
  • access to treatment

Mentioned in this episode

Organizations: American Psychological Association

Books & works: Engage and Connect

More episodes of On the Mind with The Weill Cornell Medicine Department of Psychiatry

Explore listener stats, chart rankings, contacts and more on the On the Mind with The Weill Cornell Medicine Department of Psychiatry podcast page.