S17 Ep18: Metastatic Bladder Cancer 2026 UPDATE

About this episode

This episode reviews the management of metastatic urothelial carcinoma, highlighting the shift in treatment paradigms and the importance of understanding trial data.

Two Onc Docs , hosted by Samantha A. Armstrong, MD, and Karine Tawagi, MD, is a podcast dedicated to providing current and future oncologists and hematologists with the knowledge they need to ace their boards and deliver quality patient care. Dr Armstrong is a hematologist/oncologist and assistant professor of clinical medicine at Indiana University Health in Indianapolis. Dr Tawagi is a hematologist/oncologist and assistant professor of clinical medicine at the University of Illinois in Chicago. In this episode, OncLive On Air ® partnered with Two Onc Docs to provide a comprehensive review of metastatic urothelial carcinoma management, contrasting historical standards with the rapidly evolving frontline paradigm. As the field transitions into a new era of care, Drs Armstrong and Tawagi emphasized the importance of understanding trial data and toxicity management for both board preparation and clinical practice. The discussion began with details about the historical treatment paradigm, which relied on platinum-based chemotherapy followed by maintenance avelumab for patients who did not progress. However, the experts noted that the current SOC has shifted dramatically following…

People in this episode

Hosts: Samantha A. Armstrong, MD, Karine Tawagi, MD

Topics covered

• metastatic bladder cancer
• urothelial carcinoma
• oncology
• clinical practice
• trial data
• toxicity management

Keywords

• metastatic bladder cancer
• urothelial carcinoma
• oncology
• EV-302 trial
• enfortumab vedotin
• pembrolizumab
• toxicity management
• clinical practice

Mentioned in this episode

Organizations: Indiana University Health, University of Illinois

Products: enfortumab vedotin, pembrolizumab

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