201. Back to Basics - Advanced Gastric/GOJ Cancer

201. Back to Basics - Advanced Gastric/GOJ Cancer

From Oncology for the Inquisitive Mind by Michael Fernando and Josh Hurwitz

May 17, 2026 · 28 min · Season 4 · Episode 17

About this episode

The episode discusses advanced gastric and GOJ cancer, focusing on emerging treatments and immunotherapy.

On today's episode, Josh and Michael "advance" in their ongoing GI journey, as Michael continuously insists on saying, to discuss advanced gastric and GOJ cancer. Historically, an orphan disease with a very poor prognosis, perhaps the first rays of light are beginning to shine on this difficult-to-treat cancer type. Immunotherapy has been well established as standard of care, but are there any new agents that are emerging in this space? As always, the answer to that question is "yes," and as usual, the agent in question is trastuzumab deruxtecan. Listen on for all the surprising details, even more awful puns, and a strange tangent about the difference between a "good" and "effective" dictator. Studies discussed in this episode: Checkmate 648 / 649 Destiny-Gastric01 For more episodes, resources and blog posts, visit www.inquisitiveonc.com Please find us on Twitter @InquisitiveOnc! If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.com Art courtesy of Taryn Silver Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/ Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice…

People in this episode

Hosts: Michael Fernando, Josh Hurwitz

Topics covered

  • advanced gastric cancer
  • GOJ cancer
  • immunotherapy
  • trastuzumab deruxtecan
  • oncology
  • medical research

Keywords

  • gastric cancer
  • GOJ cancer
  • immunotherapy
  • trastuzumab deruxtecan
  • oncology
  • Checkmate 648
  • Checkmate 649
  • Destiny-Gastric01

Sponsors

Pfizer, Merck Pharmaceuticals

Mentioned in this episode

Products: trastuzumab deruxtecan

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