About this episode

This episode features an interview with Dr. Jamie E Chaft discussing nonmetastatic non-small cell lung cancer and various treatment approaches.

Featuring an interview with Dr Jamie E Chaft, including the following topics: Case: A man in his early 70s with a 40 to 50 pack-year history of smoking and cT2bN1 squamous cell carcinoma of the lung with PD-L1 60% treated with induction therapy and surgery (00:00) Available clinical data with immunotherapy in the neoadjuvant, perioperative and adjuvant settings (07:45) Factors in the selection of adjuvant immunotherapy, including circulating tumor DNA (11:39) Evolving approaches to management, including systemic therapy, surgery and radiation therapy techniques (19:28) Case: A woman in her early 60s with nonmetastatic non-small cell lung cancer (NSCLC) and an EGFR exon 19 deletion who is enrolled in the NeoADAURA study (24:03) Importance of clinical trials in the adjuvant setting (33:02) Data surrounding treatment in the neoadjuvant setting; key implications of the NeoADAURA study (35:41) Case: A man in his late 60s with a history of smoking and Stage III T4N3 NSCLC not otherwise specified with low PD-L1 expression, high tumor mutation burden, microsatellite stability and an STK11 mutation (41:34) Selecting patients for the NeoADAURA study treatment approach; deciding between…

People in this episode

Host: Dr. Neil Love

Guest: Dr Jamie E Chaft

Topics covered

• Non-Small Cell Lung Cancer
• Immunotherapy
• Adjuvant Therapy
• Clinical Trials
• Case Studies
• Treatment Approaches

Keywords

• non-small cell lung cancer
• immunotherapy
• adjuvant therapy
• NeoADAURA study
• case studies
• circulating tumor DNA
• treatment approaches

Mentioned in this episode

Organizations: NeoADAURA

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