Ep42: Pain is More Than What the Knee Looks Like: Osteoarthritis Pain Mechanisms and Phenotypes with Dr. Lisa Carlesso

Ep42: Pain is More Than What the Knee Looks Like: Osteoarthritis Pain Mechanisms and Phenotypes with Dr. Lisa Carlesso

August 30, 2025 · 1h 1m · Episode 42

About this episode

This episode discusses the complexities of knee osteoarthritis pain and the importance of pain phenotyping.

In this episode, we talked about The relationship between knee osteoarthritis (OA) pain and the stages of knee OA The different experiences of knee OA pain Pain phenotyping using Quantitative Sensory Testing and self-reported measures Dr. Lisa Carlesso is a an associate professor in the School of Rehabilitation Science at McMaster University in Canada with training as a clinical epidemiologist and a physical therapist. Her research program is broadly focussed on understanding the mechanisms and consequences of musculoskeletal pain with a particular focus on OA joint pain. Her research strives to optimize outcomes for people with chronic musculoskeletal disorders by 1. Understanding the complex mechanisms of acute and persistent pain through pain phenotyping to improve prognosis and treatment, 2. Using the understanding of endogenous modulation of pain to enhance conservative treatment options and 3. Improving the clinical measurement of pain. Resources Aoyagi, K., et al. (2022). Does weight-bearing versus non-weight-bearing pain reflect different pain mechanisms in knee osteoarthritis?: the Multicenter Osteoarthritis Study (MOST). Osteoarthritis and cartilage, 30(4), 545-550…

People in this episode

Guest: Dr. Lisa Carlesso

Topics covered

Mentioned in this episode

Organizations: McMaster University

Books & works: Osteoarthritis and cartilage

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