Miracles of Science #3: RNA World Part 2
From Patient Empowerment Program: A Rare Disease Podcast by n-Lorem Foundation (Dr. Stan Crooke, Amy Williford, Kim Butler, Andrew Serrano, Jon Magnuson, and Kira Dineen)
May 27, 2026 · 28 min · Episode 98
About this episode
Dr. Stan Crooke explores the RNA world and its significance in cellular function and antisense therapies.
In Part 2 of the n-Lorem Patient Empowerment Program podcast Miracles of Science series on RNA, Dr. Stan Crooke further explores the fascinating “RNA world,” explaining how RNA molecules are processed, protected, modified, and used to manage cellular function. The episode breaks down concepts like pre-RNAs, poly-A tails, 5’ caps, RNA splicing, and the multiple “codes” that make RNA dynamic and information-rich — foundational science that helps power antisense therapies for nano-rare patients and helps make the RNA world a true "Miracle of Science," allowing n-Lorem to fulfil its mission. Shownotes: 0:00 — Introduction to n-Lorem Overview of the n-Lorem Foundation mission and support for nano-rare patients and families. 0:15 — Podcast & Sponsor Introduction Dr. Stan Crooke introduces the podcast and acknowledges sponsor ChemGenes. 1:17 — Entering the “RNA World” Dr. Crooke introduces RNA biology and explains why RNA science is foundational to antisense therapies. 1:31 — What Are Pre-RNAs? Explanation of immature “pre-RNAs” and how they contain instructions for cellular processing and transport. 3:31 — RNA Processing & Adding Nucleotides Discussion of how RNAs are trimmed…
People in this episode
Host: Dr. Stan Crooke
Topics covered
- RNA biology
- antisense therapies
- RNA processing
- cellular function
- nano-rare patients
Keywords
- RNA
- pre-RNAs
- poly-A tails
- RNA splicing
- cellular processing
Sponsors
ChemGenes
Mentioned in this episode
Organizations: n-Lorem Foundation
More episodes of Patient Empowerment Program: A Rare Disease Podcast
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- Realities of the Nano-rare: Episode 2 Oliver Glass · April 22, 2026 · 50 min
- Realities of the Nano-rare: Episode 1 with Sarah Glass · April 8, 2026 · 51 min
- Miracles of Science #2: Induced Pluripotent Stem Cells · March 25, 2026 · 30 min
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