
“My Brain Feels Better”
From Pediatrics Now for Parents by pediatricsnowforparents
March 10, 2026 · 44 min · Episode 115
About this episode
Lisa and Craig discuss their son Ryan's experience with PANS and the impact of immune responses on behavior.
Parents Lisa and Craig recount their son Ryan’s sudden, devastating onset of PANS—extreme OCD, emotional contamination, refusal to leave home, or even the couch. Today we’re talking about PANS and PANDAS. These are conditions in which a child’s immune response to an infection—sometimes strep—can trigger sudden changes in behavior or psychiatric symptoms like anxiety, obsessive-compulsive behaviors, or tics. It’s uncommon, but when it happens the changes can be dramatic, which is why awareness among parents and pediatricians is important. Immunologist Dr. Anthony Infante describes using targeted autoimmune testing (Cunningham panel) and IVIG antibody infusions, which gradually restored Ryan’s sleep, hygiene, and social life and ultimately returned him to a healthy, functioning young adult.
People in this episode
Hosts: Lisa, Craig
Guest: Dr. Anthony Infante
Topics covered
- PANS
- PANDAS
- OCD
- immune response
- behavioral changes
- pediatric health
Keywords
- PANS
- PANDAS
- OCD
- immune response
- behavioral symptoms
- IVIG
- Cunningham panel
- pediatric health
Mentioned in this episode
Organizations: Cunningham panel
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