Modafinil (Provigil)

About this episode

This episode explores the nuanced use of Modafinil in psychiatry.

Welcome back! Today, we are looking at Modafinil and it's nuanced use in psychiatry. References: Provigil (modafinil) [prescribing information]. North Wales, PA: Teva Pharmaceuticals USA, Inc. U.S. Food and Drug Administration. Available at: https://www.accessdata.fda.gov/drugsatfda docs/label/2015/020717s037s038lbl.pdf Schwartz JR. Modafinil in the treatment of excessive sleepiness. Drug Des Devel Ther. 2009;2:71–85. Kaplan S, Goehring EL Jr, Engel T, et al. Cardiovascular outcomes associated with modafinil in patients with obstructive sleep apnea. Pharmacoepidemiol Drug Saf. 2018;27(11):1182–1190. doi:10.1002/pds.4642 Cortese S, Adamo N, Del Giovane C, et al. Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis. Lancet Psychiatry. 2018;5(9):727–738. doi:10.1016/S2215-0366(18)30269-4 Goss AJ, Kaser M, Costafreda SG, Sahakian BJ, Fu CH. Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials. J Clin Psychiatry. 2013;74(11):1101–1107. doi:10.4088/JCP.13r08560 Bahji A…

People in this episode

Hosts: Dr. Tanner Hewitt, Dr. Larry Wang, Dr. Bradley Miller

Topics covered

• Modafinil
• psychiatry
• sleep disorders
• ADHD
• depression
• treatment efficacy

Keywords

• Modafinil
• Provigil
• psychiatry
• sleepiness
• ADHD
• depression
• treatment

Mentioned in this episode

Organizations: Teva Pharmaceuticals USA, Inc., U.S. Food and Drug Administration

Products: Modafinil

Books & works: Drug Des Devel Ther, Lancet Psychiatry, J Clin Psychiatry, J Affect Disord

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