Reinventing Cell Therapy with Acoustics

Reinventing Cell Therapy with Acoustics

From RealPharma: Conversations with Pharma Pathfinders by RealPharma

November 24, 2025 · 52 min · Season 2 · Episode 49

About this episode

This episode explores how a new acoustic-powered gene-delivery platform may redefine cell therapy.

Reinventing Cell Therapy with Acoustics, Microfluidics & High-Throughput Engineering In this episode, hosts Na-Ri Oh and Ian Wendt sit down with Dr. Andrew Gray — immune cell engineer, biotech founder, venture capitalist, and CEO of CellEcho — to explore how a new acoustic-powered gene-delivery platform may redefine the boundaries of cell therapy. The conversation spans the current state of the cell therapy landscape, the persistent barriers to scalability, and why CellEcho’s ASOP platform (Acoustically Stabilized Oscillatory Pockets) could unlock a new era of faster, cheaper, and more effective cell engineering. 🔬 Episode Highlights 1. The State of Cell Therapy: Breakthroughs & Bottlenecks Despite scientific success, many pharma companies are exiting cell therapy due to cost, complexity, and manufacturing burdens. Conversely, major players like BMS continue doubling down, acquiring companies such as Orbital Therapeutics. Autologous therapies remain logistically overwhelming and expensive—often ~$400k per dose. 2. Why Cell Therapy Is So Hard to Scale “Vein-to-vein” timelines are still measured in weeks, not days. Manufacturing is bespoke: each patient’s cells must be…

People in this episode

Hosts: Na-Ri Oh, Ian Wendt

Guest: Dr. Andrew Gray

Topics covered

  • cell therapy
  • acoustic-powered gene delivery
  • biotech innovation
  • scalability challenges
  • immune cell engineering

Keywords

  • cell therapy
  • gene delivery
  • acoustics
  • biotech
  • manufacturing challenges
  • ASOP platform
  • immune cells

Mentioned in this episode

Organizations: CellEcho, BMS, Orbital Therapeutics

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