HER2-Positive Metastatic Breast Cancer — An Interview with Prof Dr Sibylle Loibl on First-Line and Maintenance Therapy (Companion Faculty Lecture)
About this episode
The episode features an interview with Prof Dr Sibylle Loibl discussing advancements in the treatment of HER2-positive metastatic breast cancer.
Featuring a slide presentation and related discussion from Prof Dr Sibylle Loibl, including the following topics: · Overview of the changing landscape of treatment for patients with HER2-positive metastatic breast cancer (mBC) (0:00) · Results from the CLEOPATRA, PATINA and HER2CLIMB-05 trials of first-line treatment and maintenance approaches for HER2-positive mBC (5:26) · Efficacy and safety findings from the Phase III DESTINY-Breast09 trial comparing trastuzumab deruxtecan with or without pertuzumab to taxane/trastuzumab/pertuzumab as first-line therapy for HER2-positive mBC (14:56) · Predictors of long-term benefit from first-line treatment with HER2-targeted agents; contribution of pertuzumab to the efficacy of first-line HER2-targeted combination regimens (22:57) · Control of brain metastases and CNS disease with first-line HER2-targeted regimens (26:31) CME information and select publications
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