RHR: Revisiting the Gut-Immune Axis
From Revolution Health Radio by Chris Kresser
May 12, 2026 · 26 min
About this episode
Chris Kresser discusses the gut-immune axis and its impact on health, including the role of the gut microbiome and nutrition in preventing disease.
The gut-immune axis is one of the most important and most overlooked systems in human health. In this episode of Revolution Health Radio, Chris explains how the gut microbiome, intestinal barrier, and immune system work together to regulate inflammation and protect against disease. Learn how disruptions in gut health, driven by ultra-processed foods, environmental toxins, antibiotics, and chronic stress, can lead to intestinal permeability, chronic immune activation, and a wide range of conditions including autoimmune disease, skin disorders, respiratory illness, and metabolic dysfunction. Chris also breaks down the latest research on key compounds that support gut and immune health, including probiotics, prebiotics, butyrate, polyphenols, colostrum, lactoferrin, and beta glucan. Discover how targeted nutrition and lifestyle strategies can restore gut integrity, improve immune resilience, and address the root cause of chronic illness. The post RHR: Revisiting the Gut-Immune Axis appeared first on Chris Kresser .
People in this episode
Host: Chris Kresser
Topics covered
- gut health
- immune system
- inflammation
- chronic illness
- nutrition
- lifestyle strategies
Keywords
- gut microbiome
- intestinal barrier
- chronic immune activation
- ultra-processed foods
- environmental toxins
- chronic stress
- targeted nutrition
- immune resilience
Mentioned in this episode
Products: probiotics, prebiotics, butyrate, polyphenols, colostrum, lactoferrin, beta glucan
More episodes of Revolution Health Radio
- RHR: Fibermaxxing: Why the Internet’s Hottest Gut Health Trend Gets It Half Right · May 26, 2026 · 20 min
- RHR: Beyond the Headlines: A Functional Medicine Approach to Microplastics · May 5, 2026 · 30 min
- RHR: The Sleep Optimization Trap: Are You Tracking Yourself Into Worse Sleep? · April 28, 2026 · 17 min
- RHR: The GLP-1 Blind Spot: What Ozempic Won’t Do for Your Metabolic Health · April 21, 2026 · 25 min
- RHR: Shaking Up the Salt Myth · April 14, 2026 · 21 min
- RHR: Mouth Taping: Beyond the Hype—What the Science Really Says · April 7, 2026 · 17 min
Explore listener stats, chart rankings, contacts and more on the Revolution Health Radio podcast page.