When Illness Scripts Fail: A Mystery Case

When Illness Scripts Fail: A Mystery Case

From Run the List by Walker Redd, Emily Gutowski, Navin Kumar, Joyce Zhou, Blake Smith

September 30, 2025 · 15 min

About this episode

Dr. Mitchell Charap discusses a mystery case that challenges traditional diagnostic reasoning and emphasizes the importance of physical exams.

In this special episode, Dr. Mitchell Charap, longtime IM residency program director and master clinician at NYU Langone, walks us through a mystery case that defies expectations. Together, he and host Emily Gutowski explore how illness scripts can both guide and sometimes mislead our diagnostic reasoning, and why the physical exam remains an indispensable tool. Advertising Inquiries: https://redcircle.com/brands

People in this episode

Host: Emily Gutowski

Guest: Dr. Mitchell Charap

Topics covered

  • diagnostic reasoning
  • illness scripts
  • physical exam
  • medical education
  • mystery case

Keywords

  • diagnosis
  • medical mystery
  • illness scripts
  • clinical reasoning
  • physical examination

Mentioned in this episode

Organizations: NYU Langone

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