
A Mold with a Grudge
From Sidedoor by Smithsonian Institution
December 10, 2025 · 39 min · Season 12 · Episode 2
About this episode
This episode explores the story of how penicillin, the world's first antibiotic, was discovered through a collaboration during wartime.
It started with a messy lab and a mysterious mold. But turning “mold juice” into the world’s first antibiotic would take a sick policeman, a market cantaloupe, and an extraordinary wartime collaboration between scientists, governments, and industry. This is the story of how penicillin changed the world. Guests: Kevin Brown , Trust Archivist to Imperial College Healthcare NHS Trust and curator of the Alexander Fleming Laboratory Museum at St. Mary’s Hospital; author of Penicillin Man: Alexander Fleming and the Antibiotic Revolution Diane Wendt , curator in the Division of Medicine and Science at the Smithsonian's National Museum of American History
People in this episode
Guests: Kevin Brown, Diane Wendt
Topics covered
- antibiotics
- history of medicine
- scientific collaboration
- World War II
- Alexander Fleming
- penicillin
- mold
Keywords
- penicillin
- antibiotic
- Alexander Fleming
- mold
- scientific discovery
- World War II
- medicine
- history
Mentioned in this episode
Organizations: Imperial College Healthcare NHS Trust, Alexander Fleming Laboratory Museum, Smithsonian's National Museum of American History
Books & works: Penicillin Man: Alexander Fleming and the Antibiotic Revolution
Places: St. Mary’s Hospital
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