Initial Antibiotic Intervention May Have Long-Term Benefits for Uncomplicated Acute Appendicitis

Initial Antibiotic Intervention May Have Long-Term Benefits for Uncomplicated Acute Appendicitis

July 8, 2026 · 22 min · Episode 28

About this episode

This episode discusses a study on the long-term benefits of antibiotic treatment for uncomplicated acute appendicitis.

A multicenter randomized clinical trial in Finland has found that, among patients initially treated with antibiotics for uncomplicated acute appendicitis, the rate of recurrence and appendectomy at 10-year follow-up supports the use of antibiotics. In this episode, host Rick Greene, MD, FACS, talks with Paulina Salminen, MD, PhD, FACS(Hon), from the University of Turku in Finland, who is lead author of the study, Antibiotic Therapy for Uncomplicated Acute Appendicitis Ten-Year Follow-Up of the APPAC Randomized Clinical Trial, in The Journal of the American Medical Association. Talk about the podcast on social media using the hashtag #SurgicalReadings

People in this episode

Host: Rick Greene, MD, FACS

Guest: Paulina Salminen, MD, PhD, FACS(Hon)

Topics covered

Keywords

Mentioned in this episode

Organizations: University of Turku, The Journal of the American Medical Association

Places: Finland

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