An Update to the Serum-Saliva Debate for Transdermal Hormone Therapy Monitoring

An Update to the Serum-Saliva Debate for Transdermal Hormone Therapy Monitoring

May 26, 2026 · 1h 8m · Episode 155

About this episode

The episode discusses the effectiveness of different testing methods for monitoring male TRT, addressing common misconceptions about saliva testing.

Send us Fan Mail In this episode, Dr. Mark Holthouse joins Dr. Jaclyn Smeaton and DUTCH founder Mark Newman to take a closer look at a recent peer-reviewed publication from Precision Analytical, Inc. in Frontiers in Reproductive Health, examining how different testing methods hold up when it comes to monitoring male TRT in clinical practice. Their discussion also covers: Common misconceptions about how creams and gels show up in saliva testing and why the numbers can be misleadingWhat the cli...

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