E130: Telitacicept for SLE

E130: Telitacicept for SLE

From The Evidence Based Rheumatology Podcast by Michael Putman

December 22, 2025 · 13 min · Episode 131

About this episode

This episode discusses a significant RCT on the Blys/APRIL inhibitor telitacicept for SLE patients and its potential FDA implications.

Surprisingly (unbelievably?) impressive RCT evaluating the Blys/APRIL inhibitor "telitacicept" for patients with SLE (mixed SLE and SLE-LN). Very curious to see where the FDA goes with this one. Paper: https://www.nejm.org/doi/full/10.1056/NEJMoa2414719

People in this episode

Host: Michael Putman

Topics covered

  • rheumatology
  • clinical trials
  • SLE
  • telitacicept
  • FDA
  • Blys/APRIL inhibitors

Keywords

  • telitacicept
  • SLE
  • rheumatology
  • clinical trial
  • FDA
  • Blys/APRIL inhibitor

Mentioned in this episode

Organizations: FDA, SLE, SLE-LN

Products: telitacicept

Books & works: NEJM

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