E130: Telitacicept for SLE

E130: Telitacicept for SLE

December 22, 2025 · 13 min · Episode 131

About this episode

This episode discusses a significant RCT on the Blys/APRIL inhibitor telitacicept for SLE patients and its potential FDA implications.

Surprisingly (unbelievably?) impressive RCT evaluating the Blys/APRIL inhibitor "telitacicept" for patients with SLE (mixed SLE and SLE-LN). Very curious to see where the FDA goes with this one. Paper: https://www.nejm.org/doi/full/10.1056/NEJMoa2414719

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