E136: Secukinumab in PMR (REPLENISH)

E136: Secukinumab in PMR (REPLENISH)

June 15, 2026 · 14 min · Episode 137

About this episode

This episode discusses a significant trial on secukinumab for PMR and its implications for FDA approval.

Big trial this week in the NEJM investigating the IL17 inhibitor secukinumab in PMR. Well worth a read, I would bet on FDA approval in the near future. Some interesting tidbits and of course a weird safety thing we now have to grapple with. Be sure to go to boardsbank.com! Free rheumatology board review, >1000 questions! Paper: https://www.nejm.org/doi/full/10.1056/NEJMoa2602567

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