#131 Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List Part 3

#131 Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List Part 3

June 22, 2026 · 1h 6m · Season 2 · Episode 131

About this episode

Professor David Nutt ranks various drugs by their difficulty to quit based on an evidence-based harm scale.

Check out Scispace (JNGIANT20: 20% off the monthly plan or JNGIANT40: 40% off the annual plan): https://scispace.com/?via=jun1giantshoulder Professor David Nutt is a neuro­psychopharmacologist, former UK chief drug adviser, and author of Drugs Without the Hot Air, Drink?, Cannabis, and Psychedelics. After two rounds that sparked an overwhelming response, round three goes fringe — ibogaine, salvia, mescaline, peyote, GHB, xylazine, the nitazines, and the Amanita muscaria "Santa Claus" mushroom — ranking each on Nutt's evidence-based harm scale. Timestamps: 2:56 Ibogaine 7:21 Salvia 18:02 Mescaline & Peyote 23:59 San Pedro Cactus 28:55 GHB40:59 Kratom & 7-Hydroxy 46:05 Xylazine ("Tranq") 51:34 Nitazines 54:53 Amanita Muscaria ... Email for sponsorship enquiries: evan@thegiantsshoulder.com Buy Nutt's BooksDrink?: The New Science of Alcohol and Your Health: https://amzn.to/4dZTP9Z Psychedelics: The Revolutionary Drugs That Could Change Your Life―A Guide from the Expert: https://amzn.to/3SJXAX6 Drugs without the hot air: Making sense of legal and illegal drugs: https://amzn.to/4kyu7eS Cannabis (Seeing Through the Smoke): The New Science of Cannabis and Your…

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