From Inventing a Breakthrough Asthma Inhaler to Tackling 100% Artery Blockages | Sarvajna Dwivedi

About this episode

Kym McNicholas interviews Sarvajna Dwivedi about his journey from developing asthma therapies to innovating in the field of peripheral artery disease.

What does it take to go from helping millions of people breathe easier to helping patients keep their legs? Join The Heart of Innovation as Kym McNicholas talks with Sarvajna Dwivedi, Ph.D., entrepreneur, inventor, and CEO of AngioSafe, whose career has spanned some of the most challenging problems in medicine. Sarvajna co-founded Pearl Therapeutics, a company focused on breakthrough respiratory therapies that was ultimately acquired by AstraZeneca for $1.15 billion. Along the way, he helped develop inhaled therapies and drug-device combinations designed to improve the lives of patients with asthma and COPD. (AngioSafe United States) Today, his focus has shifted from the lungs to the arteries. As CEO and co-founder of AngioSafe, Sarvajna is leading the development of the Santreva-ATK Endovascular Revascularization Catheter, a novel device designed to restore blood flow through some of the most challenging chronic total occlusions (CTOs) physicians encounter in patients with peripheral artery disease (PAD). The technology is designed to cross completely blocked arteries, compress plaque, create a new channel, and restore blood flow without relying on a guidewire or external power…

People in this episode

Host: Kym McNicholas

Guest: Sarvajna Dwivedi

Topics covered

• asthma
• medical devices
• entrepreneurship
• peripheral artery disease
• innovation

Keywords

• asthma
• COPD
• medical innovation
• chronic total occlusions
• AngioSafe

Mentioned in this episode

Organizations: Pearl Therapeutics, AstraZeneca, AngioSafe, Medical Economics

Products: Santreva-ATK Endovascular Revascularization Catheter

More episodes of The Heart of Innovation with Kym McNicholas

• Surviving a Pulmonary Embolism: The Accident That Sparked a Medical Breakthrough 🩸 · June 13, 2026 · 46 min
• New Research on PAD Testing and AI · May 30, 2026 · 46 min
• Golf, fitness, diabetes reversal: Vern Glenn Explains · May 23, 2026 · 46 min
• She Lost Her Leg… And Built a Movement | The Woman Behind Less Leg More Heart · May 16, 2026 · 46 min
• A CEO's Life Long Battle With Apical Hypertrophic Cardiomyopathy · May 9, 2026 · 46 min
• A PAD Doctor Became the Patient… Here's What Happened · May 2, 2026 · 46 min