The Histamine Hack, PMDD, and Progesterone Sensitivity: What's Really Going On
About this episode
The episode explores the relationship between histamine blockers, progesterone sensitivity, and PMDD, featuring insights from Dr. Liz Bartman.
If you've been on social media lately, you've probably seen it: women swearing that a combo of Pepcid and Claritin, ordinary histamine blockers, gave them their life back during the worst days of their cycle. It sounds too simple to be real, and honestly, it kind of is. But the reason it's working for some women and doing absolutely nothing for others is the whole story, and it's a story almost nobody is explaining correctly. In this episode, I sit down with one of my all time favorite guests, Dr. Liz Bartman, to go deep into progesterone sensitivity, PMDD, premenstrual dysphoric disorder, and how it's different from garden variety PMS. If you've ever felt like a completely different person for two weeks out of every month, only to feel like yourself again the second your period starts, this episode is going to make you feel seen in a way most conversations about "hormones" never do. We get into what's actually driving PMDD for so many women: an altered GABA receptor that stops responding correctly to a calming metabolite of progesterone called allopregnanolone. We talk about why histamine surges at exactly the wrong time in your cycle, how estrogen and progesterone are pulling…
People in this episode
Host: Karen Martel
Guest: Dr. Liz Bartman
Topics covered
- histamine sensitivity
- PMDD
- progesterone sensitivity
- women's health
- menstrual cycle
- hormonal balance
Keywords
- histamine
- PMDD
- progesterone
- menstrual cycle
- women's health
- GABA receptor
- allopregnanolone
Mentioned in this episode
Organizations: Pepcid, Claritin
Products: progesterone, allopregnanolone
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