Episode 38: The one where I speak to Jeremy Starkweather and Jason Ylizarde, co-creators of the Dragonfly Cholangioscope

Episode 38: The one where I speak to Jeremy Starkweather and Jason Ylizarde, co-creators of the Dragonfly Cholangioscope

From The Interventional Endoscopist by Mankanwal Sachdev

November 18, 2025 · 1h 8m · Episode 38

About this episode

The episode discusses the development and mechanics of the Dragonfly Cholangioscope with its co-creators.

This conversation traces Dragonfly from an idea “in the back of a cab” to a clinically focused cholangioscopy platform that rotates through the biopsy channel for predictable, millimeter-level control. We delve into the mechanics (≈1.7 mm channel supporting 1.5 mm forceps and 4.5 Fr EHL), exploring how the catheter’s suppleness and internal rigidity enhance distal duct stability and device passability, and why micro-movements and neutral ergonomics are crucial for case efficiency. We map where cholangioscopy shifts the algorithm—medium/large stones, altered anatomy, tight distal duct work, and stricture evaluation with larger bites—and talk learning curve (~3–5 cases), setup tips, and the Medtronic distribution partnership. Finally: adoption math, fair-use evaluations despite contracting realities, and a look toward accessory innovation and AI-aided visualization. Key takeaways Rotation-first control → faster targeting, less wall fighting, better stability in tight anatomy. Larger working channel enables bigger biopsies and higher-energy lithotripsy. Aim for complete fragmentation in session one; repeat procedures should be the exception. Ergonomics: neutral hand position and…

People in this episode

Host: Mankanwal Sachdev

Guests: Jeremy Starkweather, Jason Ylizarde

Topics covered

Keywords

Mentioned in this episode

Organizations: Dragonfly Endoscopy, Medtronic

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