Week In Review-Get Your Bloodwork Done, Down Regulate Dopamine, Smoking Weed: Good or Bad?

Week In Review-Get Your Bloodwork Done, Down Regulate Dopamine, Smoking Weed: Good or Bad?

May 29, 2026 · 17 min · Season 6 · Episode 538

About this episode

Jason Wright discusses health testing, dopamine regulation, and marijuana reclassification in this week's review.

Week in Review: Comprehensive Health Testing, Dopamine in an Age of Abundance, and Marijuana Reclassification Concerns Jason Wright opens with reflections on how fast the year is going and a personal tradition of watching The Holiday on June 25, then shares a clip from his conversation with John Goldman, founder of Rebel Health, about how comprehensive functional-medicine testing (DEXA, VO2 max, A1C and other labs) revealed Goldman was pre-diabetic with visceral fat, fatty liver disease, and other risk markers, prompting Wright to urge listeners to get thorough testing beyond standard annual checkups. He next introduces researcher Anna Lembke on dopamine, explaining that brains wired for survival struggle in modern overabundance, leading to down-regulation of feel-good neurotransmitters and the need to intentionally seek discomfort and reduce consumption. After a sponsor message for Authentic Health, Wright discusses a Wall Street Journal opinion on the Trump administration’s move to reclassify marijuana to Schedule 3, citing a UC San Diego study of 11,000 adolescents linking pot use to impaired brain development, and argues that weed can hinder self-improvement and widen outcome…

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