Annemarie Wensing, Tommaso Clemente, and Arjen Stam on clinical management of persistent low-level viremia in people on antiretroviral therapy

Annemarie Wensing, Tommaso Clemente, and Arjen Stam on clinical management of persistent low-level viremia in people on antiretroviral therapy

July 1, 2026 · 19 min · Episode 4

About this episode

The episode discusses the clinical management of persistent low-level viremia in people on antiretroviral therapy with experts in the field.

Some people on HIV treatment have a viral load that won't fully suppress. In this episode, we speak with Annemarie Wensing (University Medical Center Utrecht in The Netherlands and Witwatersrand University in South Africa), Aryen Stam (University Medical Center Utrecht) and Tomasso Clemente (IRCCS San Raffaele Scientific Institute in Milan, Itally); authors of an international consensus published in The Lancet HIV, bringing together nearly 100 experts across six continents to tackle one of the least standardized challenges in HIV care: low-level viremia. What does the evidence actually say about risk? When should a clinician act? How to communicate a low-level viremia diagnosis to a patient? And what does this guidance mean for the people being treated in settings where resistance testing and second-line options are out of reach? Click here to read the full article: https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(26)00107-4/fulltext

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