Presented at ASCO: the first RCT of CAR T-cell therapy in solid tumours

About this episode

Changsong Qi discusses a phase 2 trial of CAR T-cell therapy for advanced gastric cancer with hosts Chloe Wilson and Ben Abbott.

Changsong Qi joins Chloe Wilson and Ben Abbott of The Lancet to discuss their recently published phase 2 randomised controlled trial investigating Claudin-18 isoform 2-specific CAR T-cell therapy for previously treated advanced gastric or gastro-oesophageal junction cancer. Read the full article: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00860-8/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lancet Continue this conversation on social! Follow us today at... https://thel...

People in this episode

Hosts: Chloe Wilson, Ben Abbott

Guest: Changsong Qi

Topics covered

• CAR T-cell therapy
• solid tumours
• randomised controlled trial
• gastric cancer
• oncology

Keywords

• CAR T-cell therapy
• solid tumours
• gastric cancer
• randomised controlled trial
• ASCO

Mentioned in this episode

Organizations: The Lancet

Books & works: Claudin-18 isoform 2-specific CAR T-cell therapy

Places: advanced gastric or gastro-oesophageal junction cancer

More episodes of The Lancet in conversation with

• Tania Nikolcheva, Gavin Giovannoni and Tharick Pascoal on the Special issue in Neurology · May 31, 2026 · 33 min
• Paul Spiegel: rethinking the humanitarian response to conflict and forced displacement · May 19, 2026 · 32 min
• Can semaglutide be used to treat alcohol use disorder? · May 2, 2026 · 32 min
• Louise Chappell and Na’ama Carlin on Personal Cancer Stories · February 3, 2026 · 31 min
• Susannah Stanway on the London Global Cancer Week · December 19, 2025 · 24 min
• Carlos Monteiro, Camila Corvalán, and Phil Baker on Ultra-Processed Foods and Human Health · December 9, 2025 · 1h 1m