
The episode explores the division among healthcare VCs, the implications of the SpaceX IPO, and frameworks for understanding competitive advantages in the AI era.
This week we dig into a piece from Halle Tecco exploring how healthcare VCs are splitting into two camps on ownership discipline as AI drives valuations to decade highs. We also break down Sam Lessin's argument that the SpaceX IPO signals the end of the DCF as the only globally scalable story of value, and what it means that minority belief systems can now pool conviction at trillion-dollar scale. We close with Sarah Guo's "The Untrainable," a sharp framework for understanding where real moats exist in the AI era and why the defensible work is exactly the stuff that can't be benchmarked. Tune in for a packed episode touching on venture math, narrative-driven markets, and what it actually takes to build something durable when the models keep getting smarter.
Hosts: Mia Farnham, Charles Hudson
Organizations: SpaceX
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