649: Why “in range” lab results aren’t the solution to longevity | Florence Comite, M.D.

About this episode

Florence Comite, M.D. discusses the limitations of traditional lab results in relation to longevity and the importance of personalized medicine.

"What we don't know CAN really hurt us, " says Florence Comite, M.D. Comite is a Yale University School of Medicine and National Institutes of Medicine trained physician-scientist, endocrinologist, and the leading voice in the field of precision medicine and healthy longevity. She was founder of the first global women only health center at Yale three decades ago and is founder of the Comite Center for Precision Medicine & Healthy Longevity in 2005, in New York, with satellite offices in Palo Alto and Miami Beach. Her new book, Invincible: Defy Your Genetic Destiny to Live Better, Longer, was published by Little, Brown Spark in April 2026. Catch this week’s episode of mindbodygreen podcast, created in sponsorship with Toyota. For vehicles designed for all that life has to offer, check out the 2026 RAV4, Sienna, Highlander, and Grand Highlander. Hop in, turn on the episode, and enjoy every mile. 00:00 - Aging starts in your thirties 01:55 - The decline of testosterone 07:29 - How genetics dictate aging 10:08 - Increasing testosterone 12:30 - Hormone therapy 17:59 - A DHEA story 20:37 - Metabolic markers 26:11 - Using a continuous glucose monitor 33:13 - Heart medication & testing…

People in this episode

Guest: Florence Comite, M.D.

Topics covered

• longevity
• precision medicine
• hormone therapy
• genetics
• metabolic health
• aging

Keywords

• longevity
• hormone therapy
• testosterone
• genetics
• metabolic markers
• personalized medicine
• Alzheimer's spectrum

Sponsors

Toyota

Mentioned in this episode

Organizations: Yale University School of Medicine, National Institutes of Medicine, Comite Center for Precision Medicine & Healthy Longevity, Little, Brown Spark

Products: Invincible: Defy Your Genetic Destiny to Live Better, Longer

Places: New York, Palo Alto, Miami Beach

More episodes of The mindbodygreen Podcast

• 653: A neurologist's honest take on Alzheimer's blood tests | Richard Isaacson, MD · June 7, 2026 · 45 min
• 652: A guide to healthy pooping | Trisha Pasricha, MD, MPH · May 31, 2026 · 44 min
• 651: 36 years of happiness research points to this | Sonja Lyubomirsky, Ph.D. · May 24, 2026 · 46 min
• 650: Is spirituality medicine? | Joshua W. Brown, Ph.D. · May 17, 2026 · 52 min
• 648: How to walk to optimize your health | Courtney Conley, D.C. · May 3, 2026 · 46 min
• 647: The new rules of heart health | Giovanni Campanile, MD & Sandra Cammarata, MD · April 26, 2026 · 52 min