
Sam Altman on Where AI Models Go Next, with Nicholas Thompson
From The Most Interesting Thing in AI by Atlantic Re:think
April 29, 2026 · 53 min
About this episode
Sam Altman discusses the future of AI, its challenges, and its societal impact in an interview with Nicholas Thompson.
OpenAI’s Sam Altman sits for an interview with Nicholas Thompson, CEO of The Atlantic, to discuss AI’s trustworthiness, its dangers, and its impact on young people. Altman also discusses his company’s pledge to “stop competing and start assisting” rival projects that approach AGI, and why he thinks we’re not there yet. In a thorough and wide-ranging conversation, Altman opens up about where he thinks AI will go next and the mysteries that he still can’t solve. Recorded at OpenAI’s offices in San Francisco. (00:00) Introduction (02:33) Is our understanding of AI keeping pace with its growth in power? (05:10) Is chain-of-thought the key to trusting a model? (11:07) Open source AI, cybersecurity, and "infected" agents (16:26) Have we hit recursive self-improvement? (19:18) What does AI do on Sam Altman's computer? (21:15) Why hasn't AI made an impact in business yet? (24:04) Will AI make the wealth gap worse? (27:01) Why do young people hate AI? (30:23) The challenges of AI sycophancy (33:36) Do you regret making AI so human-like? (36:53) Synthetic data and "mad cow disease" (39:22) The future of publishing and media (41:54) Do we need neurosymbolic AI? (43:40) Will you cooperate…
People in this episode
Host: Nicholas Thompson
Guest: Sam Altman
Topics covered
- AI trustworthiness
- AGI
- impact on young people
- AI dangers
- open source AI
- business impact of AI
Keywords
- AI
- Sam Altman
- AGI
- trustworthiness
- young people
- open source
- business impact
Mentioned in this episode
Organizations: OpenAI, The Atlantic
More episodes of The Most Interesting Thing in AI
- How AI Is Changing Code - Paul Ford with Nicholas Thompson · June 10, 2026 · 49 min
- How Science Can Fix Dishonest AI - Yoshua Bengio with Nicholas Thompson · June 3, 2026 · 51 min
- The AI Jobs Disruption - Erik Brynjolfsson with Nicholas Thompson · May 27, 2026 · 1h 2m
- The Limits of Predictive AI - Carissa Véliz with Nicholas Thompson · May 20, 2026 · 48 min
- AI Utopia or Catastrophe? Nick Bostrom with Nicholas Thompson · May 13, 2026 · 48 min
- The Case for Open-Source AI - with Nicholas Thompson and Raffi Krikorian · May 6, 2026 · 54 min
Explore listener stats, chart rankings, contacts and more on the The Most Interesting Thing in AI podcast page.