Acts 13 Bible Study: Paul’s First Missionary Journey | Set Apart for Me

Acts 13 Bible Study: Paul’s First Missionary Journey | Set Apart for Me

July 19, 2026 · 24 min · Season 8 · Episode 33

About this episode

This episode explores Acts 13, focusing on Paul's first missionary journey and the church at Antioch's response to the Holy Spirit's call to set apart leaders for God's mission.

Acts 13 begins Paul’s first missionary journey as the Holy Spirit calls the church at Antioch to set apart Barnabas and Saul for the work of spreading the gospel. But this Acts 13 Bible study is not only about missionaries leaving home. It is about a church learning to open its hands. Throughout the book of Acts, the Holy Spirit moves first and the church struggles to catch up. Philip preaches in Samaria. The Ethiopian eunuch is baptized on a desert road. Peter enters the home of Cornelius and watches the Holy Spirit fall upon the Gentiles. But in Acts 13:1–12, something changes. For the first time, a local congregation hears the Spirit before the journey begins and willingly releases its own leaders into God’s mission. “As they served the Lord and fasted, the Holy Spirit said, ‘Set apart for me Barnabas and Saul for the work to which I have called them.’” — Acts 13:2 The church at Antioch was led by an extraordinary gathering of prophets and teachers: Barnabas, Simeon called Niger, Lucius of Cyrene, Manaen, and Saul. Different histories, cultures, social positions, and personal stories had been gathered around one table by the grace of Jesus Christ. Then the Holy Spirit asked…

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