The Skincarma Pod | Ep. 71: Superoxide Dismutase (SOD): François Vix on the “Enzyme of Life,” Oxidative Stress & Skin Longevity

About this episode

Carmine Montalto interviews François Vix about the role of superoxide dismutase in skin health and aging.

Superoxide dismutase — or SOD — is one of the most important antioxidant enzymes in the body, yet it’s rarely discussed in modern skincare. Often referred to as the “enzyme of life,” SOD plays a critical role as the body’s first line of defense against oxidative stress — a key driver of skin aging, inflammation, and cellular damage. For decades, however, SOD has been considered ineffective as an oral supplement due to its instability in the digestive system. So what happens when that problem is solved? In this episode, Carmine sits down with François Vix, former L’Oréal executive and CEO of IsoCell, to explore the science behind GliSODin — a stabilized, orally bioavailable form of SOD supported by more than 40 published studies. Together, they go beyond topical skincare to unpack how oxidative stress impacts the skin at a biological level — and why the future of beauty may lie in combining internal and external approaches. You’ll learn: • What superoxide dismutase (SOD) actually does in the body;• Why oxidative stress is central to skin aging and inflammation;• The difference between antioxidant enzymes and traditional antioxidants like vitamin C;• Why SOD has historically been…

People in this episode

Host: Carmine Montalto

Guest: François Vix

Topics covered

• superoxide dismutase
• oxidative stress
• skin aging
• internal and external beauty
• antioxidant enzymes
• skin health

Keywords

• superoxide dismutase
• oxidative stress
• skin longevity
• antioxidants
• GliSODin
• skin inflammation
• oral supplements

Mentioned in this episode

Organizations: L’Oréal, IsoCell

Products: GliSODin

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