Grads boo AI, Reese Witherspoon gets dunked + Karpathy joins Anthropic | TWiAI E14

Grads boo AI, Reese Witherspoon gets dunked + Karpathy joins Anthropic | TWiAI E14

From This Week in AI by Jason Calacanis

May 20, 2026 · 1h 39m · Episode 14

About this episode

The episode discusses Andrej Karpathy's move to Anthropic, the booing of AI by graduates, and features a roundtable with industry leaders.

The frontier labs are coming for the application layer, and they're going to steal your idea. We dug into Andrej Karpathy's move to Anthropic, the new rules of AI etiquette, and why graduates are booing AI at commencement speeches. This week's roundtable: Kanjun Qiu (CEO of Imbue, building open source agents), Jeremy Fraenkel (CEO of Fundamental, large tabular models for enterprise data), and Karri Saarinen (CEO of Linear, the product development system used by OpenAI, Coinbase, Cursor, Ramp, and Cash App). Thank you to our exclusive sponsor: PayPal Open , One Platform for All Business: http://paypalopen.com/ Timestamps: 0:00 Cold open 1:02 Welcome to Episode 14 of This Week in AI 1:45 Kanjun Qiu on Imbue's GPU cluster bet that funds the company 5:38 Jeremy Fraenkel on why LLMs choke on structured enterprise data 9:36 Karri Saarinen on Linear and product work for AI agents 12:50 Design in the age of AI: why early-stage product design is getting worse 21:18 Jason coins "AI etiquette": your output is your responsibility 33:30 Andre Karpathy joins Anthropic 40:00 The cult of each AI lab: SpaceX, Anthropic, OpenAI 47:00 Anthropic's pricing misstep and the "punk…

People in this episode

Host: Jason Calacanis

Guests: Kanjun Qiu, Jeremy Fraenkel, Karri Saarinen

Topics covered

  • AI etiquette
  • Andrej Karpathy
  • graduation
  • AI application layer
  • product development
  • enterprise data
  • AI labs

Keywords

  • AI
  • Andrej Karpathy
  • graduation
  • AI etiquette
  • product development
  • enterprise data
  • AI application layer
  • Kanjun Qiu
  • Jeremy Fraenkel
  • Karri Saarinen

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Mentioned in this episode

Organizations: Anthropic, Imbue, Fundamental, Linear, OpenAI, Coinbase, Cursor, Ramp, Cash App

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