
This episode discusses recent developments in DAPT, VTE therapy, sudden cardiac death, updated heart failure definitions, and a controversial decision by NICE in the UK.
DAPT back in the news, a practice-changing trial in VTE therapy, new knowledge in sudden cardiac death, heart failure definitions updated, and a dumb decision by NICE in the UK are the topics discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only . To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Antiplatelet Therapy After Stenting DAPT-MVD Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2517588 HOST-EXAM Trial at 2 years https://pubmed.ncbi.nlm.nih.gov/34010616/ HOST-EXAM Trial at 10 years 10.1016/S0140-6736(26)00422-8 External Link Nick Kurzen on X https://x.com/ncurzen/status/2077676739463922151 II Aspirin Proves Its Mettle After Hip and Knee Replacement EPCAT III Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2603649 CRISTAL Trial https://jamanetwork.com/journals/jama/fullarticle/2795528 III New (and old) Knowledge in Sudden Cardiac Death Sudden Cardiac Death and its Relation to Cardiac Disease at Autopsy https://doi.org/10.1016/j.jacc.2026.01.029 Sudden Cardiac Death Due to MI With Obstructive and Nonobstructive Coronary Arteries https://doi.org/10.1016/j.jacc.2026.01.030…
Host: John Mandrola, MD
Organizations: NICE, Medscape
Books & works: DAPT-MVD Trial, HOST-EXAM Trial, EPCAT III Trial, CRISTAL Trial, Sudden Cardiac Death and its Relation to Cardiac Disease at Autopsy, Sudden Cardiac Death Due to MI With Obstructive and Nonobstructive Coronary Arteries, Frequency of Sudden Cardiac Death and Profiles of Risk, AHA/ACC/ESC/WHF Expert Consensus Document
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