351: Resistance Reboot
From This Week in Microbiology by Vincent Racaniello
March 6, 2026 · 59 min · Episode 351
About this episode
The episode discusses innovative methods for combating foodborne pathogens and antibiotic resistance using bacteriophage technology and gene drives.
TWiM discusses the use of bacteriophage-loaded microneedle patches for targeted and minimally disruptive foodborne pathogen decontamination, and a conjugal gene drive-like system that efficiently suppresses antibiotic resistance in bacteria. Become a patron of TWiM. Links for this episode: Bacteriophage-loaded microneedle patches for food (Sci Adv) Gene drive to suppress antibiotic resistance (npj antimicrob and resistance) CRISPR gene drives (Syntego) Bier laboratory Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv
People in this episode
Host: Vincent Racaniello
Topics covered
- bacteriophage
- microneedle patches
- foodborne pathogens
- antibiotic resistance
- gene drive
- CRISPR
Keywords
- bacteriophage
- microneedle patches
- foodborne pathogens
- antibiotic resistance
- gene drive
- CRISPR
- decontamination
Mentioned in this episode
Organizations: Bier laboratory, Sci Adv, npj antimicrob and resistance, Syntego
Books & works: Music used on TWiM
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