358: Gut Microbes and ALS

358: Gut Microbes and ALS

July 4, 2026 · 58 min · Episode 358

About this episode

The episode discusses the link between gut microbial inflammation and ALS, along with cysteine metabolism's role in Acinetobacter baumannii fitness impairment.

TWiM explains the connection between inflammation caused by microbial glycogen in the gut and amyotrophic lateral sclerosis, and how disruption of cysteine metabolism leads to synthetic lethality and in vivo fitness impairment in Acinetobacter baumannii . Become a patron of TWiM. Links for this episode: Myeloid cell gene prevents i nflammatory response to microbial glycogen (Cell Rep) Cysteine metabolism and fitness impairment in Acinetobacter baumannii (mBio) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

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