TWiN 73: The price of a bigger brain

TWiN 73: The price of a bigger brain

June 25, 2026 · 1h 27m · Episode 73

About this episode

The episode discusses the paradox of brain development and the risks associated with cell divisions in the human brain, along with the role of DNA repair pathways.

TWiN unpacks a striking paradox, that the very cell divisions that built the human brain's most advanced layers also put them at greatest risk, and how a dedicated DNA repair pathway saves them. Hosts: Vincent Racaniello , Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts , Google Podcasts , RSS Links for this episode MicrobeTV Discord Server Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair (Nature) Timestamps by Jolene Ramsey . Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

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