TWiP 279: Tolling for hookworms

TWiP 279: Tolling for hookworms

From This Week in Parasitism by Vincent Racaniello

May 1, 2026 · 51 min · Episode 279

About this episode

The episode reviews a phase 2 clinical trial of a recombinant vaccine against hookworm blood feeding.

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hookworm blood feeding. Hosts: Vincent Racaniello , Daniel Griffin , and Christina Naula Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Links for this episode Join the MicrobeTV Discord server Phase 2 hookworm vaccine clinical trial (Lancet Inf Dis) Phase 2 Schistosoma vaccine clinical trial (Vaccines) TWiP study – information and survey Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

People in this episode

Hosts: Vincent Racaniello, Daniel Griffin, Christina Naula

Topics covered

  • hookworm
  • vaccine
  • clinical trial
  • parasitism
  • blood feeding
  • enzymes

Keywords

  • hookworm
  • vaccine
  • clinical trial
  • N. americanus
  • glutathione S-transferase-1
  • parasitism

Mentioned in this episode

Organizations: N. americanus, Lancet Inf Dis, Vaccines

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