TWiV 1321: Phage cross talk and cross reactions
From This Week in Virology by Vincent Racaniello
May 10, 2026 · 1h 52m · Episode 1321
About this episode
The episode discusses the implications of cross-reactive anti-prophage antibodies and bacterial heteroresistance in phage therapeutic failure, along with how phages communicate across species.
TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Craig Venter dies (Nature) Hantavirus outbreak (WHO) Hantavirus on board (YouTube) HPS 25th anniversary discovery story (EID) Phage therapeutic failure unraveled (Nat Med) Phages communicate across species (Cell) Control of lysis-lysogeny decisions (Trends Micro) Arbitrium phages manipulate each other (Cell) Elio Schaechter on arbitrium (TWiM 146) Letters read on TWiV 1321 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Could this fungus contaminate Mars? Rich – Supernova in a Sideways Spiral Jolene – Virology class communication projects 2026 Vincent – Facts About The Boeing 747 Hump That Will Surprise You Listener Picks David – My first science video in 3 years Intro music is by Ronald Jenkees Send your virology questions and…
People in this episode
Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, Jolene Ramsey
Topics covered
- phage therapy
- cross-reactive antibodies
- bacterial heteroresistance
- microbial ecosystems
- phage communication
Keywords
- phage therapy
- anti-prophage antibodies
- bacterial heteroresistance
- microbial ecosystems
- phage communication
- Hantavirus outbreak
- supernova
- fungus contamination
Mentioned in this episode
Organizations: MicrobeTV, Nature, WHO, Nat Med, Cell, Trends Micro, TWiM
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