
MOTS-C Peptide Explained: Mitochondrial Health, Metabolic Function, and Longevity Science
From Today's discussion by Infinity Peptides
December 22, 2025 · 33 min · Episode 57
About this episode
This episode discusses the MOTS-c peptide and its implications for metabolic health and longevity.
In this episode, we deliver an in-depth, evidence-based discussion on the MOTS-c peptide , a mitochondria-derived peptide that has gained significant attention in metabolic health, insulin sensitivity, exercise performance, and longevity research. MOTS-c is unique among peptides because it is encoded by mitochondrial DNA and functions as a key regulator of cellular energy metabolism and stress adaptation. This podcast explores how MOTS-c works at the cellular level , its role in activating AMPK pathways, regulating glucose utilization, and supporting mitochondrial resilience. We examine preclinical and emerging human research on MOTS-c’s potential impact on metabolic syndrome, age-related decline, obesity, inflammation, and exercise capacity , while clearly distinguishing established science from ongoing investigation.
People in this episode
Host: Infinity Peptides
Topics covered
- MOTS-c peptide
- mitochondrial health
- metabolic function
- longevity science
- insulin sensitivity
- exercise performance
Keywords
- MOTS-c
- mitochondrial DNA
- cellular energy metabolism
- AMPK pathways
- metabolic syndrome
- obesity
- inflammation
- exercise capacity
Mentioned in this episode
Products: MOTS-c peptide
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