Bacteria 4D Simulation, Safer Large Gene Insertion, uniQure Roller Coaster

About this episode

The episode discusses advancements in bacterial simulation, gene editing technologies, and a new biomarker for dementia risk, along with updates on uniQure's stock performance.

A new study from the J. Craig Venter Institute simulates the complete life cycle of a minimal bacterial cell in 4D space and time at nanoscale resolution. Meanwhile, in gene editing, a new technology has designed DNA donors that evade the immune system, allowing safer large gene insertion that is one step closer to scalable mutation-agnostic therapies. In brain diseases, researchers have found a novel blood-based biomarker that can predict a woman’s risk of developing dementia as many as 25 years before symptoms appear. Our episode rounds out with uniQure’s roller coaster stock, following Vinay Prasad, MD, and his second departure from the FDA.   Join GEN editors Corinna Singleman, PhD, Fay Lin, PhD, Uduak Thomas and Alex Philippidis for a discussion of the latest biotech and biopharma news.    Listed below are links to the GEN stories referenced in this episode of Touching Base :    Simulating Life: 4D Whole-Cell Model of a Minimal Bacterium GEN , March 9, 2026   Safer Large DNA Insertion Moves Genetic Medicine Toward Scalability By Fay Lin, PhD, GEN , March 11, 2026 Blood Biomarker Predicts Women’s Dementia Risk Up to 25 Years Early GEN , March 10…

People in this episode

Hosts: Corinna Singleman, PhD, Fay Lin, PhD, Uduak Thomas, Alex Philippidis

Topics covered

• bacterial simulation
• gene editing
• biomarkers
• dementia risk
• biotech news
• biopharma

Keywords

• bacteria
• gene insertion
• biomarker
• dementia
• biotech
• uniQure
• FDA

Mentioned in this episode

Organizations: J. Craig Venter Institute, uniQure, FDA

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