Hairy Cell Leukemia: Strategies for Improved Patient Outcomes

Hairy Cell Leukemia: Strategies for Improved Patient Outcomes

From Treating Blood Cancers by Blood Cancer United

November 20, 2025 · 40 min

About this episode

Dr. Paul Hampel discusses strategies for improved patient outcomes in hairy cell leukemia, covering diagnostics, therapies, and emerging treatments.

Paul J. Hampel, MD, Mayo Clinic, Rochester, MN Recorded on November 4, 2025 Paul J. Hampel, MD Assistant Professor of Medicine Division of Hematology, Department of Medicine Mayo Clinic Rochester, MN In this episode, Dr. Paul Hampel from Mayo Clinic Rochester takes a comprehensive look at hairy cell leukemia (HCL). He reviews the current diagnostic work-up, including immunophenotypic and molecular testing, and highlights key clinical features that distinguish HCL from related disorders. Dr. Hampel also discusses approved frontline therapies and evidence-based approaches for relapsed or refractory disease, with attention to infection risk and supportive care. The conversation explores emerging agents, novel combinations, and clinical trials shaping the next wave of HCL management. Join us for this expert discussion, offering practical insights to enhance care and outcomes for patients with HCL.

People in this episode

Guest: Paul J Hampel Md

Topics covered

  • hairy cell leukemia
  • diagnostic work-up
  • immunophenotypic testing
  • molecular testing
  • frontline therapies
  • relapsed disease
  • supportive care
  • clinical trials

Keywords

  • patient outcomes
  • cancer treatment
  • HCL management

Mentioned in this episode

Places: Rochester, MN

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