About this episode

The episode discusses the implications of Nick Reiner's medication timeline on his defense in a high-profile murder case involving his parents.

Nick Reiner faces two counts of first-degree murder with a special-circumstance allegation of multiple murders in the stabbing deaths of his parents, filmmaker Rob Reiner, 78, and photographer Michele Singer Reiner, 70, at their Brentwood home in December 2025. He has pled not guilty. He is held without bail at Twin Towers Correctional Facility. His original defense attorney, Alan Jackson, withdrew from the case in January. A sealed medical order has been filed. He is now represented by public defender Kimberly Greene. The mental-health dimension of this case is already shaping the legal landscape. Nick Reiner has a reported schizoaffective disorder diagnosis and a documented history of addiction that includes multiple treatment facilities and periods of homelessness. Sources indicate a medication change occurred approximately a month before the alleged killings. He has been described by those with knowledge of his condition inside the facility as delusional and almost childlike — reportedly screaming innocence at night and allegedly unable to process why he is incarcerated. Retired FBI Counterintelligence Behavioral Analysis Program Chief Robin Dreeke examines what the reported…

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