About this episode

Dr. Sasha Hakman provides a comprehensive breakdown of the causes and implications of miscarriage and recurrent pregnancy loss.

Pregnancy loss affects 15–25% of clinically recognized pregnancies, yet so many people are left without answers — or without hope. In this solo episode, Dr. Sasha Hakman breaks down everything you need to know about miscarriage and recurrent pregnancy loss: the five major causes, how each one is diagnosed, what treatment actually looks like, and which lifestyle factors are (and aren't) worth worrying about. If you've experienced a loss and are searching for answers, this episode is for you — and remember, it is not your fault. In this episode, we cover: Why miscarriage is so common, and how the definition of "recurrent pregnancy loss" has evolved to include biochemical losses Bucket 1 — Genetic/Chromosomal causes: why random chromosomal errors (like trisomy 16 and Turner syndrome) account for up to 75% of losses, the U-shaped age-risk curve, and when to test for balanced translocations via karyotype Bucket 2 — Anatomic causes: uterine septums, scar tissue (Asherman syndrome), fibroids, polyps, adenomyosis, and how they're diagnosed via saline infusion sonogram or HSG Bucket 3 — Immune/Autoimmune causes: antiphospholipid syndrome (APS), the antibodies involved, and why diagnostic…

People in this episode

Host: Dr. Sasha Hakman

Topics covered

• miscarriage
• recurrent pregnancy loss
• causes of miscarriage
• diagnosis
• treatment options
• lifestyle factors

Keywords

• miscarriage
• pregnancy loss
• genetic causes
• anatomic causes
• immune causes
• endocrine causes
• unexplained pregnancy loss

Mentioned in this episode

Organizations: ASRM

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