Rosie The Dog

Rosie The Dog

From Up Against Reality by Chris Ippolito and Larry Bentley

March 31, 2026 · 39 min · Season 1 · Episode 129

About this episode

The episode discusses the intersection of AI and veterinary medicine through the story of a dog named Rosie and her cancer treatment.

A dying dog, a desperate owner, and an LLM walk into an oncology lab — and somehow it works. This week we’re still celebrating AI’s good side, alongside the usual chaos: CEO shake-ups, OpenAI’s romantic misfires, and Anthropic accidentally spilling the secrets of its most dangerous model. Disclaimer: The medical treatment discussed in this episode is anecdotal. Consult a licensed veterinary oncologist before pursuing experimental treatments for pets. LINKS MENTIONED IN THIS EPISODE The RNA Institute (UNSW):  The research facility where Rosie’s personalized mRNA vaccine was manufactured.  Learn more about the UNSW RNA Institute Google DeepMind AlphaFold:  The AI system used to model the protein structures of Rosie’s specific tumor mutations. Explore the AlphaFold Database Original News Coverage:   The Independent:   “A man used ChatGPT to help make a cancer vaccine for his dog. Here’s how” NBC News Segment:   “Australian tech entrepreneur uses AI to create cancer treatment for his dog” PODCAST INFO : Podcast Website: UpAgainstReality.com Episode link: https://upagainstreality.com/2026/03/31/rosie-the-dog/ Apple Podcasts…

People in this episode

Hosts: Chris Ippolito, Larry Bentley

Topics covered

  • AI in medicine
  • veterinary oncology
  • personalized medicine
  • technology news
  • AI advancements

Keywords

  • AI
  • veterinary oncology
  • cancer treatment
  • mRNA vaccine
  • DeepMind
  • OpenAI
  • Anthropic

Mentioned in this episode

Organizations: OpenAI, Anthropic, The RNA Institute, Google DeepMind

Books & works: The Independent, NBC News Segment

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