
Episode 66: The Agent Paradox - Why Moderna's Most Productive AI Systems Aren't Agents
From Vanishing Gradients by Hugo Bowne-Anderson
January 8, 2026 · 43 min
About this episode
Hugo Bowne-Anderson and Eric Ma discuss the limitations of AI agents in favor of reliable workflows in data science applications at Moderna.
Surprise. We don’t have agents . I actually went in and did an audit of all the LLM applications that we’ve developed internally. And if you were to take Anthropic’s definition of workflow versus agent , we don’t have agents. I would not classify any of our applications as agents. x Eric Ma , who leads Research Data Science in the Data Science and AI group at Moderna , joins Hugo on moving past the hype of autonomous agents to build reliable, high-value workflows . We discuss: * Reliable Workflows : Prioritize rigid workflows over dynamic AI agents to ensure reliability and minimize stochasticity in production environments; * Permission Mapping : The true challenge in regulated environments is security , specifically mapping permissions across source documents, vector stores , and model weights ; * Trace Log Risk : LLM execution traces pose a regulatory risk , inadvertently leaking restricted data like trade secrets or personal information ; * High-Value Data Work : LLMs excel at transforming archived documents and freeform forms into required formats, offloading significant “janitorial” work from scientists; * “Non-LLM” First : Solve problems with simpler tools like Python or ML…
People in this episode
Host: Hugo Bowne-Anderson
Guest: Eric Ma
Topics covered
- AI systems
- workflow
- reliability
- data science
- biotech
- LLMs
Keywords
- agents
- workflows
- LLMs
- data science
- biotech
- regulatory risk
- permission mapping
Mentioned in this episode
Organizations: Moderna, Anthropic
More episodes of Vanishing Gradients
- The Future of Agentic Data Science · May 25, 2026 · 1h 5m
- Agent-Harness.ipynb* · May 20, 2026 · 1h 20m
- Agentic Engineering and the Lost Art of Verification · May 12, 2026 · 1h 32m
- Next Level AI Evals for 2026 · April 23, 2026 · 54 min
- Privacy Theater Is Not Privacy Engineering: What It Actually Takes to Ship Safe AI · April 15, 2026 · 1h 7m
- LLM Architecture in 2026: What You Need to Know with Sebastian Raschka · April 13, 2026 · 1h 18m
Explore listener stats, chart rankings, contacts and more on the Vanishing Gradients podcast page.