
Cellular Senescence and the Future of Equine Osteoarthritis Management
From Veterinary Vertex by AVMA Journals
May 29, 2026 · 16 min
About this episode
Dr. Lynn Pezzanite discusses cellular senescence and its implications for managing equine osteoarthritis.
Send us Fan Mail We sit down with Dr. Lynn Pezzanite to explore a promising angle on aging-related equine osteoarthritis (OA): cellular senescence, the pro-inflammatory state where cells release a senescence-associated secretory phenotype (SASP) that can amplify damage inside tissues over time. We walk through why horses are such a valuable One Health model for osteoarthritis research and why this team compared synovial fluid cells from the joint with peripheral blood mononuclear cells from ...
People in this episode
Guest: Dr. Lynn Pezzanite
Topics covered
- equine osteoarthritis
- cellular senescence
- One Health model
- inflammation
- joint health
Keywords
- equine
- osteoarthritis
- cellular senescence
- inflammation
- joint health
- One Health
Mentioned in this episode
Organizations: AVMA Journals
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