Cellular Senescence and the Future of Equine Osteoarthritis Management

Cellular Senescence and the Future of Equine Osteoarthritis Management

From Veterinary Vertex by AVMA Journals

May 29, 2026 · 16 min

About this episode

Dr. Lynn Pezzanite discusses cellular senescence and its implications for managing equine osteoarthritis.

Send us Fan Mail We sit down with Dr. Lynn Pezzanite to explore a promising angle on aging-related equine osteoarthritis (OA): cellular senescence, the pro-inflammatory state where cells release a senescence-associated secretory phenotype (SASP) that can amplify damage inside tissues over time. We walk through why horses are such a valuable One Health model for osteoarthritis research and why this team compared synovial fluid cells from the joint with peripheral blood mononuclear cells from ...

People in this episode

Guest: Dr. Lynn Pezzanite

Topics covered

  • equine osteoarthritis
  • cellular senescence
  • One Health model
  • inflammation
  • joint health

Keywords

  • equine
  • osteoarthritis
  • cellular senescence
  • inflammation
  • joint health
  • One Health

Mentioned in this episode

Organizations: AVMA Journals

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